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TriMix Injection for ED should not be taken with the following medications: hypersensitivity or allergy to any component of this formulation; conditions predisposing you to priapism (painful erection lasting 4 hours or more): sickle cell anemia, multiple myeloma or leukemia; anatomical deformation of the ***** or penile implants; direction by your physician that sexual activity is inadvisable or contraindicated. Tell your doctor if you have a condition or are taking a medicine that interferes with blood clotting.